West Bengal Board JELET 2024 Pharmacy Question Paper with Answer
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Pharmacy Question Paper with Answer / JELET Previous Year Question Paper Solution
Category-I (Q 1 to 100) (Carry 1 mark each. Only one option is correct. Negative marks :-
1.First edition of Indian pharmacopoeia was published in
(A) 1958
(B) 1945
(C) 1955
(D) 1946
Ans: - (C) 1955
2. Ball mill works on the principle of:
(A) Attrition
(B) Compression
(C) Impact
(D) Combined impact and Attrition
Ans: - (D) Combined impact and Attrition
3. The active metabolite of spironolactone is
(A) Desmethyl spironolactone
(B) Canrenone
(C) Acetylspironolactone
(D) None of the above
Ans: - (B) Canrenone
4.Ophthalmic solution is sterilised by:
(A) Autoclave
(B) Hot air oven
(C) Gaseous sterilization
(D) Bacterial filtration
Ans: - (D) Bacterial filtration
5. Muscle 'orbicularis oculi' found in
(A) Nose
(B) Mouth
(C) Hand
(D) Eye
Ans: - (D) Eye
6. Maximum allowed % of weight variation of tablet weighing 325 mg is:
(A) 1.5%
(B) 7.5%
(C) 10%
(D) 5%
Ans: - (D) 5%
7. What is medication adherence?
(A) The ability of a patient to follow a medication regimen.
(B) The act of taking medication as prescribed.
(C) The willingness of a patient to take medication.
(D) All of the above
Ans: - (D) All of the above
8. If angle of repose is in between 25-35°, type of flow is
(A) excellent
(B) satisfactory
(C) good
(D) very poor
Ans: - (B) satisfactory
9. Most abundant type of neurone found in CNS
(A) Bipolar neurone
(B) Unipolar neurone
(C) Multipolar neurone
(D) Tetrapolar neurone
Ans: - (C) Multipolar neurone
10. Which of the following causes fruit ripening?
(A) Auxin
(B) Cytokinin
(C) Gibberellins
(D) Ethylene
Ans: - (D) Ethylene
11. HLB value of sodium Lauryl sulphate is:
(A) 6.5
(B) 13.8
(C) 25.0
(D) 40.0
Ans: - (D) 40.0
12. Blood cell that does not contain nucleus
(A) Neutrophil
(B) Monocytes
(C) Lymphocytes
(D) Erythrocytes
Ans: - (D) Erythrocytes
13. Enteric resin used for coating is:
(A) Cellulose acetate phthalate
(B) Hydroxy propyl methyl cellulose
(C) Ethyl cellulose
(D) Eudragit
Ans: - (A) Cellulose acetate phthalate
14. The most widely used diluents in tablet formulation is
(A) Dextrose
(B) Lactose
(C) MCC
(D) Starch
Ans: - (B) Lactose
15. Number of oxidative steps found Kreb's cycle
(A) 1
(B) 2
(C) 3
(D) 4
Ans: - (D) 4
16. The serum containing antibacterial antibodies is called:
(A) Antitoxin
(B) Antiserum =
(C) Toxoid
(D) Immune blood derivatives
Ans: - (B) Antiserum
17. In the formulation of suspensions, generally which types selected?
(A) Hydrophilic
(B) Hydrophobic
(C) Both
(D) None
Ans: - (C) Both
18. Oil of Wintergreen is
(A) Methyl salicylate
(B) Olive oil
(C) Salicylic acid
(D) Turpentine oil
Ans: - (A) Methyl salicylate
19. Which of the following involves utilisation of the end results of drugs in a large population?
(A) Pharmacokinetics
(B) Pharmacodynamics
(C) Pharmacoepidemiology
(D) Pharmacogenetics
Ans: - (C) Pharmacoepidemiology
20. Which of the following methods are generally used in liquid filling?
(A) Gravimetric voda od
(B) Volumetric
(C) Constant level method
(D) All of the above
Ans: - (D) All of the above
21. Which of the following is the main symptom of congestive heart failure?
(A) Heart stops beating
(B) Increases in blood pressure
(C) Acute chest pain
(D) Congestion of lungs
Ans: - (C) Acute chest pain
22. Co-enzyme A is formed from
(A) Niacin leg
(B) Riboflavin
(C) Pantothenic acid
(D) Folic acid
Ans: - (C) Pantothenic acid
23. Which of the following body function is regulated by the thyroid producing hormones ?
(A) Digestion
(B) Temperature
(C) Metabolism
(D) Blood Pressure
Ans: - (C) Metabolism
24. The first recombinant antigen vaccine approved for human use is
(A) Hepatitis B Vaccine
(B) Hib Vaccine
(C) DPT Vaccine
(D) OPV
Ans: - (A) Hepatitis B Vaccine
25. Formation of glucose from Non-carbohydrate source is known was
(A) Glycolysis
(B) Glucogenolysis
(C) Glycogenesis
(D) Gluconeogenesis
Ans: - (D) Gluconeogenesis
26. Chemically cephalosporin
(A) 7-amino acid
(B) 7-aminocepholosporanic acid
(C) 5-cepholosporanic acid
(D) 6-amino carboxylic acid
Ans: - (B) 7-aminocepholosporanic acid
27. Which of the following is the most common of IDA in elderly?
(A) Malnutrition
(B) Chronic Kidney disease
(C) Medication side effect
(D) Gastrointestinal blood loss
Ans:- (D) Gastrointestinal blood loss
28. Metabolism of bilirubin includes
(A) Fe2+
(B) NADP
(C) NADPH2
(D) All of the Above
Ans: - (D) All of the Above
29. NLEM stands for
(A) Normal List of Essential Medicines
(B) Normal List of Emergency Medicines
(C) National List of Essential Medicines
(D) Novel List of Essential Medicines
Ans: - (C) National List of Essential Medicines
30. Which of the following drugs is administered by intra-nasal spray/application for systemic action?
(A) Phenylephrine
(B) Desmopressin
(C) Azelastine
(D) Beclomethasone dipropionate
Ans: - (B) Desmopressin
31. A slowly progressive and degenerative disease affecting the nervous system is termed :
(A) Stroke
(B) Migraine
(C) Alzheimer's disease
(D) Parkinson's disease
Ans: - (D) Parkinson's disease
32. Killer Killiani Test is specified for
(A) Aglycon part of Digitalis glycoside
(B) Glycon part of Digitalis glycoside
(C) Both Glycon & Aglycon part
(D) None of the above
Ans: - (A) Aglycon part of Digitalis glycoside
33. Chemically which of the following is a weakly acidic drug ?
(A) Atropine sulphate
(B) Chloroquine phosphate
(C) Ephedrine hydrochloride
(D) Phenytoin sodium
Ans: - (D) Phenytoin sodium
34. Which of the following is a heteroglycan ?
(A) Dextrins
(B) Agar
(C) Inulin
(D) Chitin
Ans: - (B) Agar
35. Quinine and Quinidine is differ in
(A) Chemical structure
(B) Solubility
(C) Isomerism
(D) None of the above
Ans: - (C) Isomerism
36. Photosensitive vitamin is
(A) Thiamine
(B) Riboflavin
(C) Niacin
(D) Cholecalciferol
Ans: - (B) Riboflavin
37. A non-volatile, highly lipid soluble drug is metabolized at a rate of 15% per hour. On intravenous injection it produces general anaesthesia for 10 min. Which process is responsible for termination of its action ?
(A) Metabolism in liver
(B) Plasma protein binding
(C) Excretion by kidney
(D) Redistribution
Ans: - (D) Redistribution
38. Glycosphingolipids are a combination of
(A) Ceramide with one or more sugar residues
(B) Sphingosine with galactose
(C) Glycerol with galactose
(D) Sphingosine with phosphoric acid
Ans: - (A) Ceramide with one or more sugar residues
39. It is the volume of air that passes into and out of the lungs by the most forceful inspiration and expiration.
(A) Tidal volume
(B) Vital Capacity
(C) Expiratory reserve volume
(D) None of the above
Ans: - (B) Vital Capacity
40. Barbituric acid is composed of
(A) Urea and Succinic acid
(C) Ammonia and malonic acid
(B) Urea and malonic acid
(D) Urea and maleic acid
Ans: - (C) Ammonia and malonic acid
41. Histamine is formed by the enzyme histidine decarboxylase in the presence of
(A) NAD
(B) FMN
(C) Hs-CoA
(D) B6-PO4
Ans: - (D) B6-PO4
42. How-co-solvents increase the solubility of poorly soluble drugs?
(A) By reducing the interfacial tension between the predominant aqueous solution and hydro-phobic solute
(B) By reducing the interfacial tension between solute and solvent
(C) Both
(D) None
Ans: - (C) Both
43. The most commonly occurring conjugation reaction for drugs and their metabolites is
(A) Glucuronidation
(B) Acetylation
(C) Methylation
(D) Glutathione conjugation
Ans: - (A) Glucuronidation
44. Interferon is
(A) Virus specific
(B) Bacterial product
(C) Synthetic antiviral agent
(D) Requires expression of cellular genes
Ans: - (D) Requires expression of cellular genes
45. Benzalkonium chloride is categorized as
(A) Acidic preservative
(B) Neutral preservative
(C) Mercurial preservative
(D) Quaternary ammonium compounds
Ans: - (D) Quaternary ammonium compounds
46. Intracellular concentration of sodium ion (Na+) is
(A) 5-15 mM/L
(B) 10-15 mM/L
(C) 2-5 mM/L
(D) 0-2 mM/L
Ans: - (A) 5-15 mM/L
47. Initiation of protein synthesis begins with binding of
(A) 40s ribosomal unit on mRNA
(B) 60s ribosomal unit
(C) Changing of tRNA with specific amino acid
(D) Attachment of aminoacyl tRNA on mRNA
Ans: - (A) 40s ribosomal unit on mRNA
48. Composition of glass is
(A) Sand
(B) Soda ash asthm
(C) Limestone &Cullet
(D) All of the above
Ans: - (D) All of the above
49. Phosphorylation of adenosine to AMP is catalysed by
(A) Adenosine kinase
(B) Deoxycytidine kinase
(C) Adenylosuccinase
(D) Adenylosuccinate synthetase
Ans: - (A) Adenosine kinase
50. A person returning from dinner party meets with road accident and has to be urgently operated upon under general anaesthesia. Which drug can be injected intramuscularly to hasten his gastric emptying
(A) Methylpolysiloxane
(B) Promethazine
(C) Metoclopramide
(D) Apomorphine
Ans: - (C) Metoclopramide
51. In Parkinson, there is a deficiency of
(A) GABA
(B) Acetylcholene
(C) Nor-epinephrine
(D) Dopamine
Ans: - (D) Dopamine
52. What is the significance of regularly reviewing and updating Patient Information Leaflets (PILs)?
(A) To ensure that information provided is accurate and up-to-date
(B) To reduce the risk of medication errors
(C) To comply with regulatory requirements
(D) All of the above
Ans: - (D) All of the above
53. Vincristine differs from vinblastine in the following respect
(A) Its prominent adverse effect is neuropathy
(B) It frequently produces alopecia
(C) It does not significantly depress bone marrow
(D) All of the above
Ans: - (A) Its prominent adverse effect is neuropathy
54. Which benzodiazepine is useful in the management of status epilepticus?
(A) Diazepam
(B) Alprozolam
(C) Nitrazepan
(D) Triazolam
Ans: - (A) Diazepam
55. What is the primary objective of supply chain management in hospital pharmacy?
(A) To increase the cost of drugs
(B) To reduce the cost of drugs
(C) To maintain an adequate supply of drugs
(D) To increase the sale of drugs
Ans: - (C) To maintain an adequate supply of drugs
56. Drug used to treat xerostomia
(A) Pilocarpine
(B) Carbachol
(C) Acetylcholine
(D) Edrophonium
Ans: - (A) Pilocarpine
57. Use of isoniazid is restricted due to
(A) Ototoxicity
(B) Hepatotoxicity
(C) Neurotoxicity
(D) Bone marrow depression
Ans: - (B) Hepatotoxicity
58. Bioassays are carried out to :
(A) Measure the pharmacological activity of a drug
(B) Avoid clinical trials for new drugs
(C) Detect the impurity in a given drug
(D) Screen from pharmacogenetic influences of new drugs
Ans: - (A) Measure the pharmacological activity of a drug
59. Which drug does not possess H, blocking properties but useful in peptic ulcer?
(A) Famotidine
(B) Ranitidine
(C) Omeprazole
(D) Cimetidine
Ans: - (C) Omeprazole
60. Ketoconazole contains heterocyclic ring.
(A) Imidazole
(B) Acridine
(C) Pyridine
(D) Pyrimidine
Ans: - (A) Imidazole
61. Which of the following agents shows cytotoxicity that is cell cycle specific?
(A) Dactinomycin
(B) Doxorubicin
(C) Cisplatin
(D) Methotrexate
Ans: - (A) Dactinomycin
62. Which of the following is CYP450 enzyme inhibitor?
(A) Grape juice
(B) Rifampicin
(C) Barbiturates
(D) Carbamazepine
Ans: - (A) Grape juice
63. Which type of patient is most likely to be hyper sensitive to aspirin ?
(A) Intrinsic asthmatic
(B) Extrinsic asthmatic
(C) Chronic bronchitis
(D) Patient with viral infection
Ans: - (A) Intrinsic asthmatic
64. This drug can be used to increase calcium excretion in persons with hypercalcemia.
(A) spironolactone
(B) furosemide
(C) acetazolamide
(D) mannitol
Ans: - (B) furosemide
65. Which one of these is contra indicated in the presence of active tuberculosis?
(A) Streptomycin
(B) Hydrocortisone
(C) PABA
(D) PAS
Ans: - (A) Streptomycin
66. Which of the following receptor shows the slowest response?
(A) GPCR
(B) Ion channel
(C) Enzyme linked
(D) Steroid receptor
Ans: - (D) Steroid receptor
67. The following are some of the variables to consider while choosing a vendor except
(A) Quality
(B) Price
(C) Slow delivery
(D) Assurance of supply
Ans: - (C) Slow delivery
68. ẞ lactam ring fused with oxazolidine ring is named as
(A) penam
(B) carbapenam
(C) clavam
(D) monobactam
Ans: - (B) carbapenam
69. Which of the following is not used in redox titration?
(A) Phenolphthalein
(B) 1, 10 phenanthroline
(C) Diphenylamine
(D) KMnO4
Ans: - (A) Phenolphthalein
70. Murmur is a disorder of which of the following?
(A) AV Nodes
(B) SA Nodes
(C) Heart valves
(D) Pulmonary vein
Ans: - (C) Heart valves
71. Compounds with the same chemical formula but different structural formula are known as -
(A) Aliphatic compounds
(C) Isotopes
(B) Polymers
(D) Isomers
Ans: - (D) Isomers
72. A genetically determined abnormal or unusual response to a drug
(A) Idiosyncrasy
(B) Tolerance
(C) Genetic polymorphism
(D) Salicylism
Ans: - (C) Genetic polymorphism
73. Which of the following is not an example of intravenous anaesthetics?
(A) Etomidate ketamine
(B) Fentanyl
(C) Diazepam
(D) Halothane
Ans: - (D) Halothane
74. Absorption of oral iron preparations can be facilitated by co-administering
(A) Antacids
(B) Ascorbic acids
(C) Tetracyclines
(D) Phosphates
Ans: - (B) Ascorbic acids
75. Which one among the following is a cholinesterase reactivator?
(A) Pralidoxime chloride A
(B) Endorphonium
(C) Carbachol
(D) Acetylcholine
Ans: - (A) Pralidoxime chloride A
76. Why insulin is important for our body?
(A) It helps blood sugar to enter into the cell
(B) It breaks sugar molecule in the blood
(C) It keeps our sucrose level normal
(D) It raises cholesterol level
Ans: - (A) It helps blood sugar to enter into the cell
77. Which drug is a potent inhibitor of HIV replication that acts as chain- terminator of viral DNA during reverse transcription?
(A) Ribavirin
(B) Zidovudin
(C) Remdesivir
(D) Faripiravir
Ans: - (B) Zidovudin
78. Eye pressure is measured by
(A) Sphygmanometer
(B) Opthalmoscope
(C) Tonometer
(D) Phoropter
Ans: - (C) Tonometer
79. Ex-officio member means
(A) External member
(B) Member because of "chair"
(C) Executi ve committee member
(D) Ex-member of the committee
Ans: - (B) Member because of "chair"
80. Advertisement of drugs claiming cure of disease mentioned in Schedule-J is
(A) Granted
(B) Prohibited
(C) Exempted
(D) None of above
Ans: - (B) Prohibited
81. All of the following statements concerning toxoids are true except
(A) toxoids are detoxified toxins
(B) toxoids are antigens
(C) toxoids are often available in a precipitated or adsorbed forming
(D) toxoids produce permanent immunity
Ans: - (D) toxoids produce permanent immunity
82. Lyophilization means
(A) Sterilization
(B) Freeze drying
(C) Burming of ashes
(D) Fumigation
Ans: - (B) Freeze drying
83. What is the primary muscle responsible for inspiration at rest?
(A) Diaphragm.
(B) Intercostal muscle
(C) Abdominal muscle
(D) Pectoral muscle
Ans: - (A) Diaphragm.
84. According to Biopharmaceutics Classification System, Class IV drugs have
(A) High Solubility/High Permeability
(B) Low Solubility/High Permeability
(C) High Solubility/Low Permeability
(D) None of the above
Ans: - (D) None of the above
85. Schedule P deals with the
(A) Prescription drugsled
(B) Life Period of drugs
(C) Caution on the label
(D) Packing of drugs
Ans: - (B) Life Period of drugs
86. Which among the following is an essential amino acid for human?
(A) Alanine
(B) Glutamic acid
(C) Serine
(D) Valine
Ans: - (D) Valine
87. What is the size range of microspheres ?
(A) 1-1000 μm
(B) 1-1000 nm
(C) 1-10 μm
(D) 0.1-10 μm
Ans: - (A) 1-1000 μm
88. Apoptosis is
(A) Programmed cell death
(B) Programmed cell regeneration
(C) All of the above.
(D) None of the above
Ans: - (A) Programmed cell death
89. Lignified trichomes are present is
(A) Nux vomica
(B) Senna
(C) Belladonna
(D) All of the above
Ans: - (C) Belladonna
90. 1-fluro 2,4-dinitrobenzene is also known as
(A) Sanger's reagent
(B) Sorensen's reagent
(C) Edman's reagent
(D) Sakaguchi's reagent
Ans: - (D) Sakaguchi's reagent
91. Which one of these is immunomodulatory drug?
(A) Brahmi
(B) Ashwagandha
(C) Amia
(D) Digitalis
Ans: - (B) Ashwagandha
92. Seidlitz Powder is a
(A) Compounds effervescent powder
(B) Dusting powder
(C) Draught
(D) None of the above
Ans: - (A) Compounds effervescent powder
93. Syphilis caused by:
(A) Treponema pallidum
(B) Niesseria gonorrhoea
(C) Phthirus humanus
(D) None of the above
Ans: - (A) Treponema pallidum
94. Invert sugar consists of equal parts of
(A) Dextrose and laevulose
(B) Dextrose and sucrose
(C) Fructose and sucrose
(D) Glucose and fructose
Ans: - (D) Glucose and fructose
95. Intrinsic factor for absorption of iron is:
(A) Vitamin B6
(B) Vitamin D
(C) Vitamin B12
(D) Vitamin A
Ans: - (C) Vitamin B12
96. Polio virus mainly replicates in
(A) Lungs
(B) GIT
(C) Liver
(D) All of the above
Ans: - (B) GIT
97. Ascariasis is transmitted through :
(A) Contaminated water
(B) Contaminated milk
(C) Flesh food
(D) Raw vegetables & salads
Ans: - (A) Contaminated water
98. Hansen's disease is also known as
(A) Tetanus
(C) Gonorrhoea
(B) Tuberculosis
(D) AIDS
Ans: - No Options are Right (Right Anserrs is : - Leprosy)
99. A very fine powder is defined as one which can pass through sieve no :
(A) 80
(C) 120
(B) 40
(D) 20
Ans: - (C) 120
100. Captopril lowers blood pressure by :
(A) Inhibition of calcium influx
(B) Inhibition of enzyme peptidyl dipeptidase
(C) Relaxation of smooth muscle
(D) None of the above
Ans: - (D) None of the above
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